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Omics and Bioinformatics (OBICs) Core
2nd Annual Introduction to RNA-seq Workshop
Dr. Armand Bankhead III
On Thursday, August 9th and Friday, August 10th, M-LEEaD and the Rogel Cancer Center presented a joint workshop to provide an introduction to RNA-sequencing analysis at the School of Public Health. This was our 2nd Annual Introduction to RNA-seq Workshop, and although only 30 seats were available, we had over 100 students, post-docs, faculty, and staff registered to attend! The purpose of the workshop was to equip researchers with a basic understanding of RNA-Seq experimental design, data QC, processing, analysis, and visualization, with a focus on cancer research. Secondarily, it also promoted awareness of the Omics and Bioinformatics (OBICs) Core of the M-LEEaD Center and the Biostatistics, Analytics, and Bioinformatics Shared Resource (BABSR) of the Rogel Cancer Center, and offered opportunities to network between the centers.

Dr. Maureen Sartor, lead of the OBIC and faculty member of BABSR in Computational Medicine and Bioinformatics, presented best practices for experimental design and pathway analysis. Dr. Tingting Qin, member of BABSR, gave an overview of data quality control measures and how to interpret them. Dr. Hui Jiang, faculty member of BABSR in Biostatistics, lectured on methods of expression quantification and differential expression. Dr. Armand Bankhead III, also a member of BABSR, presented material on genomic annotation, use of TCGA data and hands-on R exercises. The workshop incorporated beginner hands-on exercises using R, which allowed participants to apply concepts discussed in class to example data sets. Instructors provided introductions to online tools for bioinformatics analysis such as the Database for Annotation, Visualization and Integrated Discovery (DAVID), cBioPortal, Integrative Genomics Viewer (IGV) and the UCSC genome browser. We would like to thank all instructors and coordinators for their efforts to make this event a huge success!

The instructor in the photo is Dr. Armand Bankhead III. 

          10/02/2018 - 4:00 pm - 5:00 pm - Forum Hall, Palmer Commons      
Nikki Silvestri
"Building an Inclusive, Collaborative Movement Toward Health Equity"
Register here:
Cosponsored by: Community Engagement Core and Integrated Health Sciences Core
UM SPH Water Summit Keynote Speaker

          10/09/2018 - Noon - Room 3755 SPH I     
Seth Guikema, PhD 
Assoc Professor, Dept Industrial & Operations Engineering, and Civil & Environmental Engineering
Working Title: "Health Impacts of Drinking Water Pipe Breaks"
Integrated Health Sciences Core
      10/23/2018 - Noon - Room 3755 SPH I     
 Joe Austin, JD, LL.M  
Asst Director, Regulatory Operation, UM Medical School Office of Research
"Changes to NIH's Common Rule for Protecting Research Study Participants: what every researcher needs to know"
Integrated Health Sciences Core

          10/30/2018 - 9 am - 10 am - Forum Hall, Palmer Commons     
Susan Buchanan, MD, MPH
Assoc Director, Great Lakes Center for Children's Environmental Health, PEHSU; U of IL, Chicago
"The Health Effects of Children's Exposure to Environmental Toxicants"
Administrative Core Fall Seminar Series

          11/06/2018 - Noon - Room 3755 SPH I     
Courtney Carignan, PhD 
Asst Professor of Food Science and Human Nutrition, Pharmacology and Toxicology, MSU
"Flame Retardants in Gymnasts"
Integrated Health Sciences Core

          11/19/2018 - Noon - Room 1680 SPH I     
Almudena Veiga-Lopez, DVM, PhD
Asst Professor of Animal Science, Reproductive and Developmental Sciences, Toxicology, MSU
"Gestational bisphenols: is the placenta at risk?"
Administrative Core Fall Seminar Series

          11/20/2018 - TBD - TBD     
Humberto Lugo
Air Monitoring Manager, Comité Civico Del Valle, Inc
Edmund Seto, PhD 
Assoc Professor, Environmental & Occupational Health Sciences, University of Washington

"Community-based Environmental Monitoring for Public Health Action: The Imperial County Community Air Monitoring Network"
Integrated Health Sciences Core & Community Engagement Core

          12/04/2018 - Noon - Room 3755 SPH I     
Andrea Cassidy-Bushrow, PhD 
Assoc Scientist, Dept of Public Health Sciences, Henry Ford Health System & CURES Center
Integrated Health Sciences Core

          12/11/2018 - Noon - Room 3755 SPH I     
Jane Hoppin, ScD 
Deputy Director, Center for Human Health & Environment, Assoc Prof Dept Biological Sciences, N Carolina State U
Integrated Health Sciences Core

          02/13/2019 - TBD - Room TBD      
Susan Nagel, PhD
Associate Professor, Obstetrics, Gynecology and Women's Health,
University of Missouri School of Medicine

"Endocrine and developmental effects of chemicals used in natural gas extraction"  
Paige Lawrence, PhD
Professor and Chair, Environmental Health Sciences Center,
University of Rochester Medical Center

“Exposure to water contaminants associated with unconventional oil and gas extraction affects the immune system."
Winter Seminar Series with ETEP Symposium

As part of a broad institutional initiative in integrative biosciences and environmental health sciences, Wayne State University (WSU) and the Institute of Environmental Health Sciences (IEHS) are recruiting up to three faculty positions (tenured or tenure-track, open rank). The program in environmental health sciences fosters interdisciplinary, integrative, and collaborative approaches to environmental disease prevention with primary areas for recruitment as follows:
• environmental epidemiology
• mechanisms underlying environmental exposure-mediated toxicities
• life-course factors affecting environmental health risk
• predictive modeling of toxicant exposure and health outcomes

Description of how to apply:
Competitive recruitment packages are available with salary and faculty rank based on qualifications. Applicants are encouraged to apply to posting #043725 through the WSU Online Hiring System Applications will be accepted until positions are filled, but for full consideration this fall, application materials should be submitted by November 30, 2018. Applications should include a curriculum vitae and a brief narrative cover letter addressed to the Director of IEHS and the Vice President for Research, indicating the applicant’s potential for research synergy within the CURES environmental health science programs and the broader institutional initiative in integrative biosciences.


Description of position:

Recent Publications citing M-LEEaD:

Montrose L, Padmanabhan V, Goodrich JM, Domino SE, Treadwell MC, Meeker JD, Watkins DJ, Dolinoy DC. Epigenetics. 2018;13(3):301-309. doi: 10.1080/15592294.2018.1448680. Epub 2018 Apr 18.

Gronlund CJ, Sheppard L, Adar SD, O'Neill MS, Auchincloss A, Madrigano J, Kaufman J, Diez Roux AV. Vulnerability to the Cardiovascular Effects of Ambient Heat in Six U.S. Cities: Results from the Multi-Ethnic Study of Atherosclerosis (MESA). Epidemiology. 2018 Aug 14. doi: 10.1097/EDE.0000000000000910. [Epub ahead of print] PubMed PMID: 30113342.

Wang W, Moroi S, Bakulski K, Mukherjee B, Weisskopf MG, Schaumberg D, Sparrow D, Vokonas PS, Hu H, Park SK. Bone Lead Levels and Risk of Incident Primary Open-Angle Glaucoma: The VA Normative Aging Study. Environ Health Perspect. 2018 Aug 8;126(8):087002. doi: 10.1289/EHP3442. eCollection 2018 Aug. PubMed PMID: 30102601; PubMed Central PMCID: PMC6108844

Laubach ZM, Perng W, Dolinoy DC, Faulk CD, Holekamp KE, Getty T. Epigenetics and the maintenance of developmental plasticity: extending the signalling theory framework. Biol Rev Camb Philos Soc. 2018 Aug;93(3):1323-1338. doi: 10.1111/brv.12396. Epub 2018 Jan 21. PubMed PMID: 29356358.

Rocco SA, Koneva L, Middleton LYM, Thong T, Solanki S, Karram S, Nambunmee K, Harris C, Rozek LS, Sartor MA, Shah YM, Colacino JA. Cadmium Exposure Inhibits Branching Morphogenesis and Causes Alterations Consistent With HIF-1α Inhibition in Human Primary Breast Organoids. Toxicol Sci. 2018 Aug 1;164(2):592-602. doi: 10.1093/toxsci/kfy112. PubMed PMID: 29741670; PubMed Central PMCID: PMC6061678.

Veiga-Lopez A, Pu Y, Gingrich J, Padmanabhan V. Trends Endocrinol Metab. 2018 Sep;29(9):607-625. doi: 10.1016/j.tem.2018.06.003. Epub 2018 Jul 13. Review. PMID: 30017741.
The Great Lakes Center for Children’s Environmental Health/Region 5 Pediatric Environmental Health Specialty Unit is hosting a conference on reproductive environmental health on October 10. Please share the below information with resident physicians, healthcare providers, students, and anyone that might be interested.

Registration Link:

Event Date:
October 10, 2018

Learning Objectives:
1.) Apply screening and reporting criteria to prenatal patients to determine need for and management of blood lead levels.

2.) Identify common environmental exposures that potentially threaten the health and wellness of our patients and their offspring.

3.) Describe how prenatal exposure to natural and synthetic estrogens target the fetal prostate epithelium

4.) Apply knowledge from today’s presentations to improve screening for toxic environmental exposures in your practice.

5.) Utilize recommended resources to refer your patients for more information about toxic environmental exposure.

Wayne State's Center for Urban Responses to Environmental Stressors (CURES) and the Barbara Ann Karmanos Cancer Institute would like to invite you to attend this year's symposium,  "The Environment and Cancer Disparities: Complex Interactions Among Multilevel, Co-Occurring Exposures". All are welcome and registration is free.

Event Date:
October 5, 2018

Registration Deadline: 
October 1, 2018

Registration Link:
Deadline for abstracts has been extended for the Sustainability and Development Conference.

They welcome abstracts for oral presentations, lightning talks, panel sessions, posters, and workshops. Abstracts must address a conference theme and follow the abstract guidelines. The submission of full papers (from those whose abstracts are accepted) will be strongly encouraged, and the best 25 papers will be published as a special issue.


Event Dates:
November 9-11, 2018

Sustainable development, as a concept and call to action to end poverty, protect the planet, and guarantee human well-being, is perhaps the greatest challenge facing humanity. The complexity of the meanings of sustainable development have meant that many scholars, researchers, decision makers, and practitioners see in it diverse ways in which to aspire for and achieve societal goals. Scholarly research, student training, and new opportunities for meaningful change continue to increase, especially with the United Nations-sponsored Sustainable Development Goals finding traction with governments and NGOs alike.In collaboration with the journal World Development, this international conference on Sustainability and Development seeks to bring together a diverse and interdisciplinary constituency to engage with the best approaches and means to implement the Sustainable Development Goals and assess progress towards them.

Please pass this on to anyone you think would benefit or contribute. 
WASHINGTON, DC – Witnesses are expected to testify at an upcoming Senate subcommittee hearing on the impacts of per- and polyfluoroalkyl substances (PFAS).   The hearing will take place on Wednesday, September 26th at 2:30 PM, the hearing will be livestreamed on the Subcommittee’s website,


Panel I
Peter C. Grevatt, Ph.D.
Office of Ground Water and Drinking Water
Office of Water, U.S. Environmental Protection Agency

Maureen Sullivan
Deputy Assistant Secretary of Defense, Environment, Safety & Occupational Health
Office of the Assistant Secretary of Defense, Energy, Installations & Environment, U.S. Department of Defense

Linda S. Birnbaum, Ph.D., D.A.B.T., A.T.S.
Director, National Institute of Environmental Health Sciences and National Toxicology Program
National Institutes of Health, U.S. Department of Health and Human Services

Brian J. Lepore
Director, Defense Capabilities and Management
U.S. Government Accountability Office

Panel II
Andrea Amico
Testing for Pease

Arnold Leriche
Community Co-Chair
Wurtsmith Restoration Advisory Board

Timothy Putnam Jr.
Vice President, Tidewater Federal Firefighters Local F-25
International Association of Fire Fighters

The EPA has launched a redesigned to the website.  You can locate air quality monitors near you with their interactive map.  Learn more about the updates here,

Click here for a PDF with useful information about NIH Public Access Policy regarding citing the center grant.

Per NIH grants policy, all publications, press releases, and other documents relevant to research funded by the center must include a specific acknowledgement of support. For the EHS Core Center, this statement may read:

“Support for this research was provided by grant P30ES017885 from the National Institute of Environmental Health Sciences, National Institutes of Health. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.”
Michigan Center on Lifestage Environmental Exposures and Disease (M-LEEaD)

School of Public Health | Copyright © 2018 Regents of the University of Michigan

Support for this center is provided by grant P30ES017885 from the National Institute of Environmental Health Sciences, National Institutes of Health

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M-LEEaD · 1415 Washington Heights · Ann Arbor, Mi 48109 · USA

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