Tony Bennett, DetroitStockCity.com

Funded Pilot Projects

If your pilot project appears below you can update your project here (intranet, for U-M personnel only).

January 2018

“MI-Environment: Heat Stress Vulnerability Rapid Response”
Primary Investigator: Patricia D Koman
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“Targeted metabolomics analysis of amniotic fluid to identify new TCE actions in a rat model of fetal growth restriction”
Primary Investigator: Rita Loch-Caruso
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“Single Cell Transcriptomics to Map the Effects of Developmental Lead Exposure on the Hippocampus”
Primary Investigator: Kelly  Bakulski, Justin Colacino
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“Single cell mapping of the human placenta for identifying environmentally sensitive cell populations”
Primary Investigator: Kelly Bakulski
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“Geospatial Analysis of Air Pollution Exposures During Pregnancy: Ambient Air Pollution and Wildland Fire Smoke Modeling ”
Primary Investigator: Patricia Koman
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“Impact of exposome on maternal and fetal steroidal milieu”
Primary Investigator: Vasantha Padmanabhan
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“Evaluating the Association between Biomarkers of Parabens and Phenol Exposure and Recurrence in ER-Positive Breast Cancer Patients”
Primary Investigator: Justin Colacino
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“Developing Effective Training Approaches to Reduce Chemical Exposures Among Nail Salon Workers ”
Primary Investigator: Marie-Anne Rosemberg
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“Toxicant Impacts on Exosomal Cell-Cell Communication between Immune and Placental Cells”
Primary Investigator: Rita Loch-Caruso
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“Neighborhood Noise Prediction Models for Epidemiology Studies of Chronic Health Across the Life-Course: Which Ones Work?”
Primary Investigator: Sara Adar
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May 2017

“Placental Epigenomics for Environmental Health Research”
Primary Investigator: Jaclyn Goodrich
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“Health Risks to Vulnerable Populations from Exposures to Airborne Asbestos from the Demolition of Abandoned Homes in Detroit ”
Primary Investigator: Richard Neitzel
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“Increasing Climate Resiliency in Detroit through the Co-Analysis of Survey Data ”
Primary Investigator: Larissa Larsen
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January 2017

“Impact of exposome on maternal and fetal inflammasome  ”
Primary Investigator: Vasantha Padmanabhan
Co-Investigator: Charles Burant, MD, PhD Robert C. and Veronica Atkins Professor of Metabolism Professor of Internal Medicine (Metabolome) Jaclyn Goodrich, PhD Research Assistant Professor of Environmental Health Sciences Univ. of Michigan School of Public Health (epigenetics)
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“Understanding the combined effects of breastmilk PCB exposure and maternal metabolic disease on infant growth outcomes ”
Primary Investigator: Brigid Ellen Gregg
Co-Investigator: Lindsay Ellsworth-Fellow in Neonataology, Department of Pediatrics Role: will be carrying out proposed sample extractions and analyses
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“Climate and cardiopulmonary health: Does excess weight enhance risk? ”
Primary Investigator: Patricia Koman
Co-Investigator: 1) Ricardo de Majo, geospatial analyst, Health Behavior Health Education, acquire and analyze data 2) Dr. Marie O'Neill, Associate Professor, Epidemiology and Environmental Health Sciences, Integrated Health and Statistics Center Core services provider
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“Alteration of epigenomic reprogramming of normal human breast stem cells by cadmium ”
Primary Investigator: Justin Colacino
Co-Investigator: Lada Koneva (Research Fellow, Department of Computational Medicine and Bioinformatics). Dr. Koneva will be responsible for the integrated analysis of the transcriptomic and epigenomic data generated in this proposal.
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“Particulate Matter Induced DNA Methylomic Changes in Bronchial Epithelial Cells”
Primary Investigator: Steven Huang
Co-Investigator: Maureen Sartor Associate Professor of Computational Medicine and Bioinformatics, Medical School and Associate Professor of Biostatistics, School of Public Health Omics and Bioinformatics Core Lead and Collaborator
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“Evaluation of Placental Responses to Environmental Toxicants Using Metabolomic and Transcriptomic Approaches”
Primary Investigator: Rita Loch-Caruso
Co-Investigator: Sean Harris, Postdoctoral Fellow, Environmental Health Sciences Elana Elkin, Graduate Student, Environmental Health Sciences Anthony Su, Graduate Student, Environmental Health Sciences
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January 2016

“MI-Environment: Promoting climate-related health within Michigan’s vulnerable communities”
Primary Investigator: Natalie Sampson
Co-Investigator: Trish Koman
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“External proficiency testing of heavy metal assessment for epidemiologic studies in the Study of Women’s Health Across the Nation (SWAN)”
Primary Investigator: Sung Kyun Park
Co-Investigator: Stuart Batterman
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“Epigenetic modifications and altered gene expression induced by source-specific air born fine particles in human lung cells”
Primary Investigator: Andrew Ault
Co-Investigator: Ying-Hsuan Lin
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“Creating fine spatial resolution air pollution and temperature data for linking to Michigan birth outcomes”
Primary Investigator: Marie O’Neill
Co-Investigator: Amy Schulz, Carina Gronlund, Veronica Berrocal, Ricardo de Majo
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“Measurements of PBDE Levels in a population-based sample of lupus patients and controls in Southeastern Michigan”
Primary Investigator: Emily Somers
Co-Investigator: Siobán D. Harlow, Stuart Batterman
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“Are sex differences in effects of early obesogen exposure on metabolic outcomes in adolescence mediated by genome-wide DNA methylation?”
Primary Investigator: Karen Peterson
Co-Investigator: Jaclyn Goodrich, Wei Perng, Peter Song
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January 2015

“Methylmercury and gene‐specific DNA methylation of CD4+ T cells in lupus”
Primary Investigator: Emily Somers, PhD, ScM
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“In Vivo Monitoring of Toxicant-Induced Placental Aging in Mice”
Primary Investigator: Rita Loch-Caruso, PhD; Steven Domino, MD, PhD
Co-Investigator: Kelly Hogan, PhD; Mark Chames, MD
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“Transcriptional and Post-Transcriptional Effects of Mutations and Environmental Factors Associated with Autism”
Primary Investigator: Mats Ljungman, PhD
Co-Investigator: Donna Martin, MD
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“Addressing Public Health Issues within the Detroit Blight Elimination Program: Transforming Health Data into Action and Policy”
Primary Investigator: Eden Wells, MD, MPH, FACPM
Co-Investigator: Regina Royan, Doug Strane
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January 2014

“Epigenetic Effects of Prenatal Environmental Exposures”
Primary Investigator: Margit Burmeister, PhD; Betsy Lozoff, MD
Co-Investigator: Dana Dolinoy, PhD; John Meeker, PhD, Maureen Sartor, PhD; Peter Song, PhD; Jie Shao, MD
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“Tissue Specific Epigenetic Alterations and Birth Outcomes Following Perinatal Bispehnol A (BPA) Exposure”
Primary Investigator: Vasantha Padmanabhan
Co-Investigator: Dana Dolinoy, PhD
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“A Pilot Study for Multiple Pollutant Exposures and Ovarian Aging”
Primary Investigator: Sung Kyun Park, PhD
Co-Investigator: Sioban Harlow, PhD; Bhramar Mukherjee, PhD; Stuart Batterman, PhD
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“The Influence of Prostaglandin E2 and Transforming Growth Factor-ß1 on DNA Methylation Patterns in Idiopathic Pulmonary Fibrosis”
Primary Investigator: Steven Huang, PhD
Co-Investigator: Maureen Sartor, PhD
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November 2012

“The interplay of heavy metals and gut microbiome on epigenetic modification”
Primary Investigator: Chuanwu Xi, PhD; Dana Dolinoy, PhD
Co-Investigator: Christopher Faulk, PhD; Jianfeng Wu, PhD
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“Genome-wide DNA methylation changes in Behçet’s disease monocytes”
Primary Investigator: Amr Sawalha, PhD
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“Epigenetics and Mercury Exposure in the American Dental Association Cohort”
Primary Investigator: Niladri Basu, PhD; Dana Dolinoy, PhD
Co-Investigator: Al Franzblau, PhD
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“Mother and Child Environmental (Mace) Cohort – Epigenetic Changes Associated With Ambient Pollution”
Primary Investigator: Stuart Batterman, PhD
Co-Investigator: P. Reddy, PhD; N. Naidoo, PhD
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February 2012

“Effect of in utero BPA exposure on allergen-induced pulmonary inflammation in adult mice”
Primary Investigator: Peter Mancuso, PhD
Co-Investigator: Edmund O’Brien, PhD
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“The role of environmental toxicants in the dysregulation of microRNAs leading to amyotrophic lateral sclerosis”
Primary Investigator: Raymond Yung, MB, ChB and Eva L. Feldman MD, PhD
Co-Investigator: Brian Christopher Callaghan, MD; Claudia Figueroa-Romero, PhD; Junguk Hur, PhD
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“Probing Trichloroethylene Embryotoxicity in the Mouse: Searching for Mechanistic Fidelity between Gene Expression and DNA Methylation using a Genome-Wide Expression and Tiling Array Approach”
Primary Investigator: Dana Dolinoy, PhD and Craig Harris, PhD
Co-Investigator: Bhramar Mukherjee, PhD; Jung Hei (Julie) Kim, PhD; Karilyn E. Sant, MPH
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“In Utero Lead Exposure and Neuron-specific Epigenetic Change Associated with Life-Course Neurobehavioral Phenotypes”
Primary Investigator: Dana Dolinoy, PhD
Co-Investigator: Christopher Faulk, PhD; Howard Hu, MD, ScD; Karen E. Peterson, ScD; Brisa N. Sanchez, PhD
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“Prenatal Bisphenol-A Exposure and Overeating on Metabolic Homeostasis”
Primary Investigator: Almudena Veiga-Lopez, DVM, PhD
Co-Investigator: Vasantha Padmanabhan, PhD
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